STAT-ERA-SEP -- All players in database
Regular season
| Primary |
| Name | Name | ERA |
| Earl Johnson* | Royal Giants | 1.96 |
| Spud Chandler | Grays | 2.28 |
| Max Lanier* | Rugrats | 2.35 |
| Whit Wyatt | Carp | 2.55 |
| Larry French* | Thunderbolts | 2.63 |
| Sid Hudson | Blues | 2.68 |
| Bob Feller | Rugrats | 2.68 |
| Elmer Riddle | Rugrats | 2.72 |
| Luke Hamlin | Hudys | 2.81 |
| Al Benton | Hawks | 3.01 |
| Ernie White* | Grays | 3.01 |
| Dutch Leonard | Panthers | 3.07 |
| Johnny Lanning | Grays | 3.15 |
| Mickey Harris* | Thunderbolts | 3.19 |
| Johnny Gorsica | Thunderbolts | 3.19 |
| Harry Gumbert | Hawks | 3.20 |
| Bob Muncrief | Natti Bohs | 3.22 |
| Atley Donald | Aces | 3.24 |
| Jim Tobin | Grays | 3.27 |
| Thornton Lee* | Rugrats | 3.28 |
| Dick Newsome | Carp | 3.33 |
| Tiny Bonham | Stampers | 3.34 |
| Johnny Vander Meer* | Carp | 3.36 |
| Curt Davis | Rugrats | 3.36 |
| Johnny Allen | Thunderbolts | 3.36 |
| Manny Salvo | Blues | 3.37 |
| Bobo Newsom | Blues | 3.40 |
| Johnny Niggeling | Arsenal | 3.45 |
| Ted Lyons | Natti Bohs | 3.45 |
| Al Smith* | Aces | 3.46 |
| Lon Warneke | Grays | 3.47 |
| Red Ruffing | Hawks | 3.50 |
| Cy Blanton | Panthers | 3.52 |
| Bill Lee | Hawks | 3.53 |
| Mort Cooper | Royal Giants | 3.59 |
| Charlie Wagner | Royal Giants | 3.62 |
| Al Milnar* | Hudys | 3.66 |
| Claude Passeau | Arsenal | 3.67 |
| Kirby Higbe | Natti Bohs | 3.74 |
| Max Butcher | Carp | 3.78 |
| Johnny Podgajny | Stampers | 3.79 |
| Bob Harris | Stampers | 3.79 |
| Rip Sewell | Aces | 3.80 |
| Vern Olsen* | Aces | 3.84 |
| Bill Dietrich | Blues | 3.85 |
| Marius Russo* | Arsenal | 3.85 |
| Ken Heintzelman* | Thunderbolts | 3.92 |
| Steve Sundra | Stampers | 3.94 |
| Vern Kennedy | Royal Giants | 4.02 |
| Ken Chase* | Panthers | 4.07 |
| Bucky Walters | Muck Dogs | 4.09 |
| Tommy Bridges | Natti Bohs | 4.10 |
| Bill Beckmann | Hawks | 4.15 |
| Bill McGee | Royal Giants | 4.24 |
| Hal Newhouser* | Panthers | 4.26 |
| Tom Earley | Hudys | 4.28 |
| Denny Galehouse | Natti Bohs | 4.43 |
| Jack Knott | Aces | 4.50 |
| Eddie Smith* | Muck Dogs | 4.53 |
| Johnny Rigney | Panthers | 4.60 |
| Hugh Casey | Hawks | 4.62 |
| Phil Marchildon | Blues | 4.64 |
| Paul Derringer | Hudys | 4.65 |
| Jim Bagby | Stampers | 4.66 |
| Hal Schumacher | Arsenal | 4.79 |
| Lefty Gomez* | Arsenal | 4.93 |
| Carl Hubbell* | Thunderbolts | 4.98 |
| Lefty Grove* | Hudys | 5.01 |
| Dick Errickson | Muck Dogs | 5.09 |
| Jack Wilson | Stampers | 5.20 |
| Cliff Melton* | Grays | 5.31 |
| Tommy Hughes | Muck Dogs | 5.73 |
| Al Javery | Muck Dogs | 6.15 |